Bladder Pain and Endometriosis: The Overlooked Connection with Interstitial Cystitis

For many living with endometriosis, the challenges don’t end with period pain or fatigue. Some also experience ongoing bladder pain, constant trips to the bathroom, and burning sensations that can be mistaken for a urinary tract infection. In many cases, these symptoms are actually caused by interstitial cystitis (IC), also known as bladder pain syndrome.

At Endometriosis Canada, we believe it’s important to talk about this often overlooked connection because recognizing it early can lead to better care and less suffering.

What is Interstitial Cystitis?

Interstitial cystitis is a chronic condition that causes bladder pressure, pelvic pain, and frequent or urgent urination. Unlike a UTI, there’s no infection causing it—and antibiotics don’t help. People with IC may feel like they constantly have to pee, even if their bladder isn’t full, and may experience sharp pain or burning during urination or sex.

How is IC Linked to Endometriosis?

IC and endometriosis often go hand in hand. Research suggests that up to 8 out of 10 people with endometriosis also experience symptoms of IC. The two conditions can mimic each other or occur side by side, making diagnosis tricky.

Some people go years thinking they have recurring infections or that their bladder pain is “just part of having endo.” In reality, they may be living with both conditions and not getting the right treatment.

Though we don’t fully understand why these two conditions are so closely linked, they may share underlying causes like inflammation or nerve sensitivity. In some cases, endo lesions near the bladder may directly trigger symptoms that feel like IC.

Why It Matters

When IC is overlooked in people with endometriosis, treatments often fall short. Addressing only one condition may leave the other unmanaged, leading to continued pain and frustration. That’s why a whole-body, team-based approach to pelvic pain is essential—one that includes gynecologists, urologists, pelvic floor physiotherapists, and pain specialists.

What You Can Do

Pay attention to your bladder symptoms. If you’re dealing with urinary urgency, burning, or bladder pain that doesn’t go away, even when tests are clear, bring it up with your doctor.

Ask about IC. If you already have an endometriosis diagnosis, mention IC to your care team. Getting the full picture is key to feeling better.

Advocate for full-spectrum care. A multidisciplinary approach helps uncover overlapping issues like IC, especially when endo treatment alone isn’t enough.

You’re not alone. Many people with endometriosis experience bladder issues, and your symptoms are valid. Getting the right diagnosis and support can be life-changing.

At Endometriosis Canada, we're committed to raising awareness of complex, overlapping conditions like IC and endometriosis. Through education, advocacy, and better medical training, we can improve outcomes and lives.